Opiniones Lehninger Principles of Biochemistry (International Edition)

Description Lehninger Principles of Biochemistry is #1 bestseller for the introductory biochemistry course because it brings clarity and coherence to an often unwieldy discipline, offering a thoroughly updated survey of biochemistry’s enduring principles, definitive discoveries, and groundbreaking new advances with each edition. This new Seventh Edition maintains the qualities that have distinguished the text since Albert Lehninger’s original edition—clear writing, careful explanations of difficult concepts, helpful problem-solving support, and insightful communication of contemporary biochemistry’s core ideas, new techniques, and pivotal discoveries. Again, David Nelson and Michael Cox introduce students to an extraordinary amount of exciting new findings without an overwhelming amount of extra discussion or detail. And with this edition, W.H. Freeman and Sapling Learning have team up to provide the book’s richest, most completely integrated text/media learning experience yet, through an extraordinary new online resource: SaplingPlus. Nelson is Professor in the Department of Biochemistry at the University of Wisconsin, Madison. He is also the Academic Program Director for university`s Institute for Cross-college Biology Education. Contents 1. The Foundations of Biochemistry 1.1 Cellular Foundations 1.2 Chemical Foundations Box 1-1 Molecular Weight, Molecular Mass, and Their Correct Units Box 1-2 Louis Pasteur and Optical Activity: In Vino, Veritas 1.3 Physical Foundations Box 1-3 Entropy: Things Fall Apart 1.4 Genetic Foundations 2. Water 2.1 Weak Interactions in Aqueous Systems 2.2 Ionization of Water, Weak Acids, and Weak Bases 2.3 Buffering agains pH Changes in Biological Systems Box 2-1 Medicine: On Being One`s Own Rabbit (Don`t Try This at Home!) 2.4 Water as a Reactant 2.5 The Fitness of Aqueous Environment for Living Organisms 3. Amino Acids, Peptides, and Proteins 3.1 Amino Acids Box 3-1 Methods: Absorption of Light by Molecules: The Lambert-Beer Law 3.2 Peptides and Proteins 3.3 Working with Proteins 3.4 The Structure of Proteins: Primary Structure Box 3-2 Consensus Sequences and Sequence Logos 4. The Three-Dimensional Structure of Proteins 4.1 Overview of Protein Structure 4.2 Protein Secondary Structure Box 4-1 Methods: Knowing the Right Hand from the Left 4.3 Protein Tertiary and Quaternary Structures Box 4-2 Permanent Waving Is Biochemical Engineering Box 4-3 Why Sailors, Explorers, and College Students Should Eat Their Fresh Fruits and Vegetables Box 4-4 The Protein Data Bank Box 4-5 Methods: Methods for Determining the Three-Dimensional Structure of a Protein 4.4 Protein Denaturation and Folding Box 4-6 Medicine: Death by Misfolding: The Prion Diseases 5. Protein Function 5.1 Reversible Binding of a Protein to a Ligand: Oxygen-Binding Proteins Box 5-1 Medicine: Carbon Monoxide: A Stealthy Killer 5.2 Complementary Interactions between Proteins and Ligands: The Immune System and Immunoglobulins 5.3 Protein Interactions Modulated by Chemical Energy: Actin, Myosin, and Molecular Motors 6. Enzymes 6.1 An Introduction to Enzymes 6.2 How Enzymes Work 6.3 Enzyme Kinetics as an Approach to Understanding Mechanism Box 6-1 Transformations of the Michaelis-Menten Equation: The Double-Reciprocal Plot Box 6-2 Kinetic Tests for Determining Inhibition Mechanisms Box 6-3 Curing African Sleeping Sickness with a Biochemical Trojan Horse 6.4 Examples of Enzymatic Reactions 6.5 Regulatory Enzymes 7. Carbohydrates and Glycobiology 7.1 Monosaccharides and Disaccharides Box 7-1 Medicine: Blood Glucose Measurements in the Diagnosis and Treatment of Diabetes Box 7-2 Sugar Is Sweet, and So Are . . . a Few Other Things 7.2 Polysaccharides 7.3 Glycoconjugates: Proteoglycans, Glycoproteins, and Glycolipids 7.4 Carbohydrates as Informational Molecules: The Sugar Code 7.5 Working with Carbohydrates 8. Nucleotides and Nucleic Acids 8.1 Some Basics 8.2 Nucleic Acid Structure 8.3 Nucleic Acid Chemistry 8.4 Other Functions of Nucleotides 9. DNA-Based Information Technologies 9.1 Studying Genes and Their Products Box 9-1 A Powerful Tool in Forensic Medicine 9.2 Using DNA-Based Methods to Understand Protein Function 9.3 Genomics and the Human Story Box 9-2 Medicine: Personalized Genomic Medicine Box 9-3 Getting to Know the Neanderthals 10. Lipids 10.1 Storage Lipids